author = "Santos, Caroline Peripolli dos and Londero, James Eduardo Lago and 
                         Santos, Maur{\'{\i}}cio Beux dos and Feltrin, Rayana dos Santos 
                         and Loebens, Luiza and Moura, Livia Bataioli and Cechin, Sonia 
                         Zanini and Schuch, Andr{\'e} Passaglia",
          affiliation = "{Universidade Federal de Santa Maria (UFSM)} and {Instituto 
                         Nacional de Pesquisas Espaciais (INPE)} and {Instituto Nacional de 
                         Pesquisas Espaciais (INPE)} and {Instituto Nacional de Pesquisas 
                         Espaciais (INPE)} and {Universidade Federal de Santa Maria (UFSM)} 
                         and {Universidade Federal de Santa Maria (UFSM)} and {Universidade 
                         Federal de Santa Maria (UFSM)} and {Instituto Nacional de 
                         Pesquisas Espaciais (INPE)}",
                title = "Sunlight-induced genotoxicity and damage in keratin structures 
                         decrease tadpole performance",
              journal = "Journal of Photochemistry and Photobiology B: Biology",
                 year = "2018",
               volume = "181",
                pages = "134--142",
                month = "Apr.",
             keywords = "UV radiation, DNA damage, DNA repair, Keratin damage, Mortality, 
                         Amphibian decline.",
             abstract = "The increased incidence of solar ultraviolet (UV) radiation, an 
                         environmental genotoxic agent, due to ozone depletion or 
                         deforestation may help to explain the enigmatic decline of 
                         amphibian populations in specific localities. In this work, we 
                         evaluated the importance of DNA repair performed by photolyases to 
                         maintain the performance of treefrog tadpoles after acute and 
                         chronic treatments with environmental-simulated doses of solar UVB 
                         and UVA radiation. Immediately after UV treatments, tadpoles were 
                         exposed to a visible light source to activate photolyases or kept 
                         in dark containers. The biological effects of UV treatments were 
                         evaluated through morphological, histological, locomotor and 
                         survival analyzes of Boana pulchella tadpoles (Anura: Hylidae). 
                         The results indicate that tadpole body weight suffered influence 
                         after both UVB and UVA treatments, although the body length was 
                         bit affected. The locomotor performance of UVB-exposed tadpoles 
                         was significantly reduced. In addition, UVB radiation induced a 
                         severe impact on tadpole skin, as well as on keratinized 
                         structures of mouth (tooth rows and jaw), indicating that these 
                         should be important effects of solar UV radiation in the reduction 
                         of tadpole performance. Furthermore, photolyases activation was 
                         fundamental for the maintenance of tadpole performance after 
                         chronic UVB exposures, but it was relatively inefficient after 
                         acute exposures to UVB, but not to UVA radiation. Therefore, this 
                         work demonstrates how the UV-induced genotoxicity and structural 
                         alterations in the skin and oral apparatus affect tadpole 
                         performance and survival.",
                  doi = "10.1016/j.jphotobiol.2018.03.013",
                  url = "http://dx.doi.org/10.1016/j.jphotobiol.2018.03.013",
                 issn = "1011-1344",
             language = "en",
           targetfile = "santos_sunligth.pdf",
        urlaccessdate = "25 jul. 2021"