@Article{SilvaZanVicCorFat:2014:DiPuAd,
               author = "Silva, Tiago Almeida and Zanin, Hudson and Vicentini, Fernando 
                         Campanh{\~a} and Corat, Evaldo Jos{\'e} and Fatibello-Filho, 
                         Orlando",
          affiliation = "{Universidade Federal de S{\~a}o Carlos (UFSCar)} and {Instituto 
                         Nacional de Pesquisas Espaciais (INPE)} and {Universidade Federal 
                         de S{\~a}o Carlos (UFSCar)} and {Instituto Nacional de Pesquisas 
                         Espaciais (INPE)} and {Universidade Federal de S{\~a}o Carlos 
                         (UFSCar)}",
                title = "Differential pulse adsorptive stripping voltammetric determination 
                         of nanomolar levels of atorvastatin calcium in pharmaceutical and 
                         biological samples using a vertically aligned carbon 
                         nanotube/graphene oxide electrode",
              journal = "Analyst",
                 year = "2014",
               volume = "139",
               number = "11",
                pages = "2832--2841",
             abstract = "A novel vertically aligned carbon nanotube/graphene oxide 
                         (VACNT-GO) electrode is proposed, and its ability to determine 
                         atorvastatin calcium (ATOR) in pharmaceutical and biological 
                         samples by differential pulse adsorptive stripping voltammetry 
                         (DPAdSV) is evaluated. VACNT films were prepared on a Ti substrate 
                         by a microwave plasma chemical vapour deposition method and then 
                         treated with oxygen plasma to produce the VACNT-GO electrode. The 
                         oxygen plasma treatment exfoliates the carbon nanotube tips 
                         exposing graphene foils and inserting oxygen functional groups, 
                         these effects improved the VACNT wettability (super-hydrophobic) 
                         which is crucial for its electrochemical application. The 
                         electrochemical behaviour of ATOR on the VACNT-GO electrode was 
                         studied by cyclic voltammetry, which showed that it underwent an 
                         irreversible oxidation process at a potential of +1.08 V in pHcond 
                         2.0 (0.2 mol L -1 buffer phosphate solution). By applying DPAdSV 
                         under optimized experimental conditions the analytical curve was 
                         found to be linear in the ATOR concentration range of 90 to 3.81 × 
                         103 nmol L-1 with a limit of detection of 9.4 nmol L-1. The 
                         proposed DPAdSV method was successfully applied in the 
                         determination of ATOR in pharmaceutical and biological samples, 
                         and the results were in close agreement with those obtained by a 
                         comparative spectrophotometric method at a confidence level of 
                         95%. © the Partner Organisations 2014.",
                  doi = "10.1039/c4an00111g",
                  url = "http://dx.doi.org/10.1039/c4an00111g",
                 issn = "0003-2654 and 1364-5528",
                label = "scopus 2014-05 SilvaZanVicCorFat:2014:DiPuAd",
             language = "en",
        urlaccessdate = "18 jun. 2024"
}