| 1. Identity statement | |
| Reference Type | Journal Article |
| Site | mtc-m16c.sid.inpe.br |
| Holder Code | isadg {BR SPINPE} ibi 8JMKD3MGPCW/3DT298S |
| Identifier | 6qtX3pFwXQZGivnK3Y/UzxVG |
| Repository | sid.inpe.br/mtc-m18@80/2008/06.26.17.21 (restricted access) |
| Last Update | 2008:06.26.17.21.58 (UTC) administrator |
| Metadata Repository | sid.inpe.br/mtc-m18@80/2008/06.26.17.22.01 |
| Metadata Last Update | 2018:06.04.04.05.16 (UTC) administrator |
| Secondary Key | INPE--PRE/ |
| DOI | 10.1140/epjst/e2008-00489-1 |
| ISSN | 1434-6060 |
| Citation Key | RossiPaivSilvBarj:2008:PhStPe |
| Title | Photoacoustic study of percutaneous absorption of Carbopol and transdermic gels for topic use in skin  |
| Year | 2008 |
| Month | Jan. |
| Access Date | 2024, Apr. 28 |
| Secondary Type | PRE PI |
| Number of Files | 1 |
| Size | 141 KiB |
| 2. Context | |
| Author | 1 Rossi, R. C. P. 2 Paiva, R. F. 3 Silva, Marcos Dias da 4 Barja, P. R. |
| Resume Identifier | 1 2 3 8JMKD3MGP5W/3C9JHQB |
| Group | 1 2 3 LAS-CTE-INPE-MCT-BR |
| Affiliation | 1 Instituto de Pesquisa & Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP) 2 Instituto de Pesquisa & Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP) 3 Instituto Nacional de Pesquisas Espaciais (INPE) 4 Instituto de Pesquisa & Desenvolvimento (IP&D), Universidade do Vale do Paraíba (UNIVAP) |
| Journal | Journal of Physics D: Applied Physics |
| Volume | 153 |
| Number | 1 |
| Pages | 479-482 |
| History (UTC) | 2008-06-26 17:22:01 :: simone -> administrator :: 2010-05-11 01:22:22 :: administrator -> simone :: 2010-05-18 12:57:22 :: simone -> administrator :: 2012-07-14 19:50:52 :: administrator -> banon :: 2008 2012-09-27 17:46:37 :: banon -> administrator :: 2008 2018-06-04 04:05:16 :: administrator -> marciana :: 2008 |
| 3. Content and structure | |
| Is the master or a copy? | is the master |
| Content Stage | completed |
| Transferable | 1 |
| Content Type | External Contribution |
| Abstract | Topical medicine application has been used to treat a good number of pathological processes. Its efficacy is associated to an efficient penetration of the drug in the internal skin layers, promoting systemic effects and excluding the possibility of drug degradation by the digestive tract and hepatic elimination. This work analyzes the penetration kinetics of two soluble bases employed as vehicles for topic application: superficial gel (Carbopol 940) and transdermic (transdermal) gel. Analysis was performed with the photoacoustic technique, based upon the absorption of modulated light by a sample with subsequent conversion of the absorbed energy in heat, generating acoustic waves in the air layer adjacent to the sample. Each of the two vehicles was evaluated through in vivo (human skin) and in vitro application. Measurements in vitro employed samples of VitroSkin (synthetic material with properties similar to those of real skin, employed in the pharmaceutical industry research). Results show that the permeation was faster for the transdermal gel, both for in vivo and in vitro measurements, indicating that in vitro measurements may be utilized in qualitative, comparative permeation studies. |
| Area | FISMAT |
| Arrangement | urlib.net > Produção anterior à 2021 > LABAS > Photoacoustic study of... |
| doc Directory Content | access |
| source Directory Content | there are no files |
| agreement Directory Content | there are no files |
| 4. Conditions of access and use | |
| Language | en |
| Target File | photoacoustic.pdf |
| User Group | administrator banon simone |
| Visibility | shown |
| Archiving Policy | denypublisher denyfinaldraft12 |
| Read Permission | deny from all and allow from 150.163 |
| 5. Allied materials | |
| Next Higher Units | 8JMKD3MGPCW/3ESR3H2 |
| Dissemination | WEBSCI; PORTALCAPES. |
| Host Collection | sid.inpe.br/mtc-m18@80/2008/03.17.15.17 |
| 6. Notes | |
| Empty Fields | alternatejournal archivist callnumber copyholder copyright creatorhistory descriptionlevel documentstage e-mailaddress electronicmailaddress format isbn keywords label lineage mark mirrorrepository nextedition notes orcid parameterlist parentrepositories previousedition previouslowerunit progress project readergroup rightsholder schedulinginformation secondarydate secondarymark session shorttitle sponsor subject tertiarymark tertiarytype typeofwork url versiontype |
| 7. Description control | |
| e-Mail (login) | marciana |
| update | |